Gadda G, Taibi A, Sisini F, Gambaccini M, Sethi SK, Utriainen DT, Haacke EM,

Zamboni P, Ursino M.
Validation of a Hemodynamic Model for the Study of the Cerebral Venous Outflow System Using MR Imaging and Echo-Color Doppler Data. AJNR

Am J Neuroradiol. 2016 Jul 21. [Epub ahead of print] PubMed PMID: 27444939


Zollino I, Zuolo M, Gianesini S, Pedriali M, Sibilla MG, Tessari M, Carinci F,
Occhionorelli S, Zamboni P.
Autologous adipose-derived stem cells: Basic science, technique, and rationale for application in ulcer and wound healing. Phlebology. 
2016 Apr 7. pii: 0268355516641546. [Epub ahead of print] PubMed PMID: 27056621

Gianesini S, GAFà R, Occhionorelli S, Menegatti E, Malagoni AM, Spath P, Lanza
G, Zamboni P.
Histologic and sonographic features of holmium laser in chronic venous disease treatment. Int Angiol. 2016 Feb 12. [Epub ahead of print] PubMed
PMID: 26871395

Zamboni P.
Is Leg Ulceration a Defending Mechanism against Toxic Iron Accumulation.
Acta Haematol. 2016;135(2):122-3. doi: 10.1159/000441214. Epub 2015
Oct 29. PubMed PMID: 26509490

Zamboni P, Tisato V, Menegatti E, Mascoli F, Gianesini S, Salvi F, Secchiero
Ultrastructure of internal jugular vein defective valves.
Phlebology. 2015 Oct;30(9):644-7. doi: 10.1177/0268355514541980. Epub 2014 Jun 27. PubMed PMID: 24972760; PubMed Central PMCID: PMC4574083

Gadda G, Taibi A, Sisini F, Gambaccini M, Sethi SK, Utriainen D, Haacke EM,Zamboni P, Ursino M.
A simulation model to study the role of the extracranial venous drainage pathways in intracranial hemodynamics.
Conf Proc IEEE Eng Med 
Biol Soc. 2015 Aug;2015:7800-3. doi: 10.1109/EMBC.2015.7320201. PubMed PMID:26738101

Gadda G, Taibi A, Sisini F, Gambaccini M, Zamboni P, Ursino M.
A new hemodynamic model for the study of cerebral venous outflow.
Am J Physiol Heart 
Circ Physiol. 2015 Feb 1;308(3):H217-31. doi: 10.1152/ajpheart.00469.2014. Epub2014 Nov 14. PubMed PMID: 25398980

Sisini F, Toro E, Gambaccini M, Zamboni P.
The Oscillating Component of the Internal Jugular Vein Flow: The Overlooked Element of Cerebral Circulation.
Neurol. 2015;2015:170756. doi: 10.1155/2015/170756. Epub 2015 Dec 9. PubMed PMID: 26783380; PubMed Central PMCID: PMC4689897

Toro EF, Muller LO, Cristini M, Menegatti E, Zamboni P.
Impact of Jugular Vein Valve Function on Cerebral Venous Haemodynamics. Curr Neurovasc Res.2015;12(4):384-97. PubMed PMID: 26256005

Gianesini S, Sisini F, di Domenico G, Menegatti E, Vannini M, Spath P, CanevaPD, Occhionorelli S, Tessari M, Gambaccini M, Zamboni P.
Lower Limbs Venous Kinetics and Consequent Impact on Drainage Direction.
J Vasc Surg Venous Lymphat
Disord. 2015 Jan;3(1):120. doi: 10.1016/j.jvsv.2014.10.014. Epub 2014 Dec 15.PubMed PMID: 26993701

Pascolo L, Gianoncelli A, Rizzardi C, Tisato V, Salomé M, Calligaro C, Salvi F, Paterson D, Zamboni P. Calcium micro-depositions in jugular truncular venousmalformations revealed by Synchrotron-based XRF imaging. Sci Rep. 2014 Oct7;4:6540. doi: 10.1038/srep06540. PubMed PMID: 25286775; PubMed Central PMCID:PMC4187013

Khare M, Singh A, Zamboni P.
Prospect of brain-machine interface in motor disabilities: the future support for multiple sclerosis patient to improve quality of life.
Ann Med Health Sci Res. 2014 May;4(3):305-12. doi:
10.4103/2141-9248.133447. Review. PubMed PMID: 24971199; PubMed Central PMCID: PMC4071724

Tisato V, Zauli G, Gianesini S, Menegatti E, Brunelli L, Manfredini R,
Zamboni P, Secchiero P.
Modulation of circulating cytokine-chemokine profile in patients affected by chronic venous insufficiency undergoing surgical hemodynamic correction.
J Immunol Res. 2014;2014:473765. doi: 10.1155/2014/473765. Epub 2014 
Mar 25. PubMed PMID: 24741602; PubMed Central PMCID: PMC3984831

Tisato V, Zamboni P, Menegatti E, Gianesini S, Volpi I, Zauli G, Secchiero P.
Endothelial PDGF-BB produced ex vivo correlates with relevant hemodynamic
parameters in patients affected by chronic venous disease.
Cytokine. 2013
Aug;63(2):92-6. doi: 10.1016/j.cyto.2013.04.018. Epub 2013 May 7. PubMed PMID:

Tisato V, Zauli G, Rimondi E, Gianesini S, Brunelli L, Menegatti E, Zamboni
P, Secchiero P.
Inhibitory effect of natural anti-inflammatory compounds on cytokines released by chronic venous disease patient-derived endothelial cells.
Mediators Inflamm. 2013;2013:423407. doi: 10.1155/2013/423407. Epub 2013 Dec 31. 
PubMed PMID: 24489443; PubMed Central PMCID: PMC3893784

Tisato V, Secchiero P, Rimondi E, Gianesini S, Menegatti E, Casciano F,
Zamboni P, Zauli G.
GM-CSF exhibits anti-inflammatory activity on endothelial cells derived from chronic venous disease patients.
Mediators Inflamm. 
2013;2013:561689. doi: 10.1155/2013/561689. Epub 2013 Nov 13. PubMed PMID:
24327798; PubMed Central PMCID: PMC3845402

Gianesini S, Tisato V, Menegatti E, Volpi I, Voltan R, Occhionorelli S,
Secchiero P, Zamboni P.
Oscillatory Turbulent Flow in Chronic Venous Disease Induces Pro-inflammatory and Reparative Biological Signaling.
J Vasc Surg Venous 
Lymphat Disord. 2013 Jan;1(1):108. doi: 10.1016/j.jvsv.2012.10.028. Epub 2012 Dec
8. PubMed PMID: 26993926

Coen M, Menegatti E, Salvi F, Mascoli F, Zamboni P, Gabbiani G,
Bochaton-Piallat ML.
Altered collagen expression in jugular veins in multiple sclerosis.
Cardiovasc Pathol. 2013 Jan-Feb;22(1):33-8. doi: 
10.1016/j.carpath.2012.05.005. Epub 2012 Jul 5. Erratum in: Cardiovasc Pathol.
2014 Mar-Apr;23(2):111. PubMed PMID: 22770861


Zamboni P.
The big idea: iron-dependent inflammation in venous disease and
proposed parallels in multiple sclerosis.
J R Soc Med. 2006 Nov;99(11):589-93.
Abstract – Full Text
Sternberg Z, Weinstock-Guttman B, Hojnacki D, Zamboni P, Zivadinov R, Chadha K, Lieberman A, Kazim L, Drake A, Rocco P, Grazioli E, Munschauer F. 
Soluble receptor for advanced glycation end products in multiple sclerosis: a potential marker of disease severity.
Mult Scler. 2008 Jul;14(6):759-63.
Abstract – Full Text
Singh AV, Zamboni P.
Anomalous venous blood flow and iron deposition in multiple sclerosis.
J Cereb Blood Flow Metab. 2009 Dec;29(12):1867-78. 
Abstract – Full Text
Uttara B, Singh AV, Zamboni P, Mahajan RT.
Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant
therapeutic options.
Curr Neuropharmacol. 2009 Mar;7(1):65-74. 
Abstract – Full Text
Zamboni P, Lanzara S, Mascoli F, Caggiati A, Liboni A.
Inflammation in venous disease.
Int Angiol. 2008 Oct;27(5):361-9. 
Abstract – Full Text
Sternberg Z, Chadha K, Lieberman A, Hojnacki D, Drake A, Zamboni P, Rocco P, Grazioli E, Weinstock-Guttman B, Munschauer F. 
Quercetin and interferon-beta modulate immune response(s) in peripheral blood mononuclear cells isolated from multiple sclerosis patients.
J Neuroimmunol. 2008 Dec 15;205(1-2):142-7. 
Abstract – Full Text
Zamboni P.
Can Facebook influence funding?
Nature. 2011 May 26;473(7348):452. 
Abstract – Full Text
Ferlini A, Bovolenta M, Neri M, Gualandi F, Balboni A, Yuryev A, Salvi F, Gemmati D, Liboni A, Zamboni P. 
Custom CGH array profiling of copy number variations (CNVs) on chromosome 6p21.32 (HLA locus) in patients with venous malformations associated with multiple sclerosis.
BMC Med Genet. 2010 Apr
Abstract – Full Text
Singh AV, Khare M, Gade WN, Zamboni P.
Theranostic implications of nanotechnology in multiple sclerosis: a future perspective.
Autoimmune Dis.
Abstract – Full Text
Singh AV, Vyas V, Montani E, Cartelli D, Parazzoli D, Oldani A, Zeri G, Orioli E, Gemmati D, Zamboni P. 
Investigation of in vitro cytotoxicity of the redox state of ionic iron in neuroblastoma cells.
J Neurosci Rural Pract. 2012
Abstract – Full Text
Gemmati D, Zeri G, Orioli E, De Gaetano FE, Salvi F, Bartolomei I, D'Alfonso S, Dall'osso C, Leone MA, Singh AV, Asselta R, Zamboni P. 
Polymorphisms in the genes coding for iron binding and transporting proteins are associated with disability, severity, and early progression in multiple sclerosis.
BMC Med Genet.
2012 Aug 10;13:70. 
Abstract – Full Text
Coen M, Menegatti E, Salvi F, Mascoli F, Zamboni P, Gabbiani G, Bochaton-Piallat ML. 
Altered collagen expression in jugular veins in multiple sclerosis.
Cardiovasc Pathol. 2013 Jan-Feb;22(1):33-8. 
Abstract – Full Text
Tisato V, Zauli G, Voltan R, Gianesini S, di Iasio MG, Volpi I, Fiorentini G, Zamboni P, Secchiero P. 
Endothelial cells obtained from patients affected by chronic venous disease exhibit a pro-inflammatory phenotype.
PLoS One.
Abstract – Full Text


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Centro Malattie Vascolari
Università degli Studi di Ferrara
Via Aldo Moro 4, Loc Cona
44124 Ferrara, Italy